I thought it would be worth creating a GitHub repository that stores this boilerplate code so that anyone can download the code and get started creating web apps with this particular technology stack.
The source comes with TypeScript, Less, Bootstrap all wired up with React and some base example components to get your started. It also sets up webpack-dev-server so you can easily spin up a local dev server to host your web app while in development.
To get started just run the following to get the code from the repository.
git clone https://github.com/leedale1981/typescript2-react15-webpack2-boilerplate.git
You should then run an NPM install to download all dependencies.
Finally you can compile the TypeScript code and run the dev server like so:
gulp webpack gulp webpack-dev-server
And thats it you should be up and running with your web app.